Sunday, April 1, 2012

The Controversy over Triclosan

Triclosan is an antimicrobial agent used in many household antibacterial products. A controversy presides over the use of this agent, however.

First, I would like to address the issues associated with Triclosan, and its function in our bodies. Triclosan blocks the active site of the enoyl-acyl carrier protein reductase enzyme. This enzyme is an essential enzyme required for the fatty acid synthesis in bacteria, and when Triclosan is present, it acts as a competitive inhibitor for the active site. As a result, the bacteria is prevented from producing the fatty acids needed for growth and reproduction, which in turn kills the bacteria. To many, this would make Triclosan a reasonable antimicrobial agent. However, some studies show that when exposed to water and UV rays, they are transformed into a potential carcinogen, Dioxin. I will need to conduct more research on this in order to understand how this occurs.

Also, this is a mental note to remember to look up the chemical structure of Triclosan and Dioxin and compare them...

1 comment:

  1. Dioxin huh? Seems crazy to me that this chemical would be included if it has the potential to become dioxin - I guess though it wouldn't surprise me either. I would say it would be very likely that these chemicals could be exposed to UV rays as well as water. Can't wait to hear more about this!

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